Volunteer for Alzheimer's research

Trial Ready Cohort for the Prevention of
Alzheimer’s Dementia (TRC-PAD)

More than 5 million Americans are living with Alzheimer’s disease. By 2050, this number is projected to rise to 14 million.

The recent tragedies of George Floyd, Ahmaud Arbery and Breonna Taylor demand that we all address the injustice in our society. These terrible events have occurred in the midst of a pandemic which is disproportionately affecting communities of color.  These events are symptoms of the unacceptable societal inequalities that contribute to poorer health for people of color in the United States.  We must be united in our pursuit of positive change.

The TRC-PAD Study Team is committed to a culture of equality, inclusiveness and diversity. Racism and other forms of discrimination will not be tolerated in any form.  We must intensify our efforts to address inequities in clinical research and work toward positive change in our society.

In our role as Alzheimer’s researchers, we will renew our commitment to unity, collaboration and collective action. We have a moral imperative to eradicate overt and implicit bias, and the conduct of rigorous clinical research demands this. We are committed to diversity in recruiting our study participants, as this is the only way we can find answers which serve the health needs of all people. A more diverse workforce enables us to have the most committed and agile minds focused on our very challenging tasks.  

We can and will do better.


The TRC-PAD Study Team

TRC-PAD Study sites have been closely monitoring the COVID-19 situation. The safety of participants and site personnel are of the utmost importance to us. Our sites will follow state and local guidance on how and when to conduct in-person research activities for the TRC-PAD Study. We ask that our current study participants stay in contact with their local site personnel to get the latest guidance and information. We will update our website with additional information as we continue to navigate this pandemic and learn more about best practices for safely conducting clinical research.

The clock is ticking. Will you join us?

The Trial Ready Cohort for the Prevention of Alzheimer’s Dementia, also known as TRC-PAD, is an observational study that aims to match people with clinical trials to prevent Alzheimer’s disease and is the next phase of the online Alzheimer Prevention Trials (APT) Webstudy.

The ‘webstudy’ is the first step in order to be invited to TRC-PAD and uses the internet to help healthy people over the age of 50 years to monitor their memory by taking online assessments every 3 months. Using the latest technology, APT Webstudy researchers monitor each participant’s quarterly results in order to identify people who may have an increased risk for developing Alzheimer’s disease.

APT Webstudy participants who experience changes in their memory or thinking ability overtime, are invited to a nearby research clinic where they are seen in-person (at no cost to them) and further evaluated for eligibility to join TRC-PAD and ultimately matched with a clinical trial. The goal of TRC-PAD is to enroll as many people as possible into clinical trials to find preventive treatments for Alzheimer’s dementia as soon as possible. We need your help.

Interested individuals should enroll in the APT Webstudy first in order to take part in TRC-PAD. To join the APT Webstudy, please visit: www.APTWebstudy.org. The website and memory tests are available in both English and Spanish.

The APT Webstudy and TRC-PAD are being conducted by the University of Southern California Alzheimer’s Therapeutic Research Institute (USC ATRI) and funded by the National Institutes of Health (NIH). 

For Researchers:

The TRC-PAD Leadership Team provides the following lists for standardized acknowledgement in publications. There are two formats for your use: